Elkhonon Goldberg, PhD is Clinical Professor in Department of Neurology, Grossman School of Medicine at New York University, and Member of the American Board of Professional Psychology in Clinical Neuropsychology.

COVID-19 may result in a wide range of neurological complications, including ischemic stroke in young people, disseminated micro hemorrhagic lesions, brain inflammation, hypoxia, various non-specific encephalopathies, focal lesions (likely to impact frontal and mesiotemporal regions) and Guillain-Barre syndrome. These are often associated with significant and lasting cognitive impairment and psychiatric symptoms. Concern has been expressed that neuro-COVID may put patients at increased risk for developing various neurodegenerative disorders later in life. It is important to recognize that these issues are real, may last for months and even years, and that they are in the patients’ brains and not just “in their heads.” Programs must be developed for long-term follow-up of these patients, with cognitive rehabilitation, psychotherapy and counseling.

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Structural changes in the putamen and pallidum in patients with long COVID fatigue.jpg

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